Chemical constituents from the stem barks of polyscias serrata balf

Plants of the genus Polyscias (the family Araliaceae) are represented as perennial shrubs and commonly cultivated in southeastern Asia Pacific regions. Pharmacological studies revealed that crude extracts their isolated compounds exhibited a variety biological activity, such antibacterial, antifungal, cytotoxic, immuno-stimulant, wound healing anti-asthmatic activities. For first time, phytochemical study on methanol (MeOH) extract stem barks Vietnamese species serrata Balf. (locally named Dinh lang rang) resulted isolation NMR (Nuclear Magnetic Resonance)-determination six 1-6. They include one nucleobase uracil (1), two nucleosides uridine (2) adenosine (3), alkaloid indole-3-carboxylic acid (4), mono-phenol glucoside koaburside (5), saponin randianin (6). The chemical structures these phytochemicals were elucidated by physicochemical, 1D-NMR [1H, 13C-NMR, DEPT (Distortionless Enhancement Polarization Transfer)], 2D-NMR [HSQC (heteronuclear single quantum coherence), HMBC (Heteronuclear Multiple Bond Correlation), COSY (correlation spectroscopy)] spectral, ESI-MS (Electron Spray Ionization-Mass Spectrum) data. This is time 2-6 have been obtained from Polyscias. In agreement with various reports, nitrogenous triterpene saponins can be seen characteristic metabolites Polyscia